Nights Edge

Nights edge is an Open discussion board
HomePortalFAQSearchMemberlistUsergroupsRegisterLog in

Display results as :
Rechercher Advanced Search
Latest topics
» muslim mantra sadhana
Fri Oct 11, 2013 6:24 am by rashid6245

» Islamic Marriage Astrology
Wed Sep 04, 2013 3:21 am by nix01

Wed Apr 25, 2012 9:40 pm by sexyonjeans

» noclegi rewal domki
Wed Aug 03, 2011 6:29 pm by Guest

» apartamenty szklarska poreba sprzedaz
Tue Aug 02, 2011 9:43 pm by Guest

» apartamenty asana bialystok
Mon Aug 01, 2011 9:42 pm by Guest

» likes for facebook pages xk
Sun Jul 31, 2011 9:05 pm by Guest

» Buy Neopoints...
Sun Jul 31, 2011 8:29 pm by Guest

» When the first Whirlpool Duet album was released in December 2001 came as a surprise to the public
Sun Jul 31, 2011 4:52 pm by Guest

free forum - FREE Search Engine Submission
Click here to submit your URL to over 8000 search engines,
directories and links pages Free. Boost your website's traffic fast!!
Our site is a forum for open discussions of all type..Handicaps and animals the list goes on..join our quiet community
Free Forum Promotion

Top List


Free Top Site

Buy Relevant Links
Buy Relevant Links

Vote For Nights Edge
at Jewell


Submit your website to 20 Search Engines - FREE with ineedhits!

Free Top Site

Advanced Anime - Anime Girls and More!

Search Engine Optimization and SEO Tools


Share | 

 check this out

Go down 

Posts : 401
Join date : 2008-07-16

PostSubject: check this out   Mon Sep 08, 2008 10:30 pm

Epilepsy Drug Linked to Bone Loss

<table cellSpacing=0 cellPadding=0 width=220 border=0><tr><td>Related Health News </TD></TR>
<tr><td id=ehs-news></TD></TR>
<tr><td id=ehs-news> </TD></TR></TABLE>

By Amanda Gardner
HealthDay Reporter
MONDAY, April 28 (HealthDay News) -- The epilepsy drug Dilantin may put young women who take it for a year or more at higher risk for osteoporosis, researchers report.
The bone loss described in a paper in the April 29 issue of Neurology was actually eight times higher than that experienced by premenopausal women who did not take any drugs for epilepsy.
"That suggests that if these women remain on this medication and have ongoing significant or accelerated bone loss that over time, they will be entering the peri-menopausal period with lower bone density and therefore a greater risk for low bone mineral density over time and therefore a higher risk of fractures," said study lead author Dr. Alison M. Pack, assistant professor of clinical neurology at Columbia University in New York City.
According to Dr. R. Eugene Ramsay, director of the International Center for Epilepsy at the University of Miami Miller School of Medicine, 90 percent of older people who have seizures are put on Dilantin, largely because it's inexpensive.
"It's particularly important, because the older population has the highest incidence of epilepsy. There are more new-onset seizures occurring there, and yet they are getting the cheapest and worst treatment," he said.
The findings are not entirely new, since previous research had already revealed an adverse effect on anti-epileptic drug treatment (Dilantin and other drugs) on bone and mineral metabolism. One previous study found that anti-seizure drugs had the same effect on the incidence of osteoporosis in older men as it did in older women, Ramsay said.
This study involved 93 premenopausal women (aged 18 to 40) with epilepsy, each of whom was taking either Dilantin (phenytoin), Tegretol (carbamazepine), Lamictal (lamotrigine) or Depakote (valproate).
The study was partially supported by GlaxoSmithKline, which makes Lamictal. Pack has also received funding from this and other pharmaceutical companies.
All participants took 1,000 milligrams of calcium a day and were physically active, both good strategies to maintain bone health.
After one year, women taking Dilantin lost 2.6 percent of their bone density in the femoral neck of the hip, while bone mineral density stayed about the same in the other three groups.
Bone mineral density stayed the same at the spine and the total hip.
The speed (one year) at which Dilantin affected bone health was surprising, said Dr. Steven V. Pacia, director of the division of neurology at Lenox Hill Hospital in New York City.
Women who need to take epilepsy drugs can either switch to a medication other than Dilantin, or they can up their intake of calcium, said Pack.
But according to Pacia, calcium supplementation may not be enough to counteract the bone-depleting effect of Dilantin.
"There may be a direct affect on bone absorption of calcium," Pacia said. "If the mechanism is damaged, the bone is not going to be able to take up calcium. An alternate drug that doesn't cause the same problem is preferable. In the rare cases we had to use [Dilantin], drugs like Fosamax and Boniva can be used to try to counteract the effect, and that does happen."
"We're just beginning to recognize that we need to look at the long-term health care issues of anti-convulsants," Ramsay said.
More information
The Epilepsy Foundation has more on this condition.
<table><tr><td id=ehs-source>SOURCES: Alison M. Pack, M.D., assistant professor, clinical neurology, Columbia University, New York City; Steven V. Pacia, M.D., director, division of neurology, Lenox Hill Hospital, New York City; R. Eugene Ramsay, M.D., director, International Center for Epilepsy, University of Miami Miller School of Medicine; April 29, 2008, Neurology </TD></TR>
<tr><td id=ehs-copyright>Copyright 2008 ScoutNews, LLC. All rights reserved. </TD></TR>
<tr><td id=ehs-brand>This is a story from HealthDay, a service of ScoutNews, LLC. </TD></TR></TABLE>

Back to top Go down
View user profile

Posts : 401
Join date : 2008-07-16

PostSubject: Re: check this out   Mon Sep 08, 2008 10:34 pm

Sorry about the way this came up but just read between the lines.. and here I have lose joint syndrome ..but I was on tegretol and dilantin for most my life.

Back to top Go down
View user profile
check this out
Back to top 
Page 1 of 1
 Similar topics
» Check my index_body template
» Spell check & word count when posting
» Two women 'caught trying to smuggle dead relative on to passenger jet at Liverpool airport'
» Check out this ranting, left-wing lunatic....
» fiona payne admits she didnt check on the baby and other terrible parenting!!!!

Permissions in this forum:You cannot reply to topics in this forum
Nights Edge :: Epilepsy-
Jump to: